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Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: the Tromsø Study 2015–2016
Open Heart ( IF 2.8 ) Pub Date : 2021-08-01 , DOI: 10.1136/openhrt-2021-001777
Amalie Nilsen 1, 2 , Tove Aminda Hanssen 3, 4 , Knut Tore Lappegård 2, 5 , Anne Elise Eggen 6 , Maja-Lisa Løchen 3, 6 , Randi Marie Selmer 7 , Inger Njølstad 6 , Tom Wilsgaard 6 , Laila A Hopstock 6
Affiliation  

Aims To compare the population proportion at high risk of cardiovascular disease (CVD) using the Norwegian NORRISK 1 that predicts 10-year risk of CVD mortality and the Norwegian national guidelines from 2009, with the updated NORRISK 2 that predicts 10-year risk of both fatal and non-fatal risk of CVD and the Norwegian national guidelines from 2017. Methods We included participants from the Norwegian population-based Tromsø Study (2015–2016) aged 40–69 years without a history of CVD (n=16 566). The total proportion eligible for intervention was identified by NORRISK 1 and the 2009 guidelines (serum total cholesterol ≥8 mmol/L, systolic blood pressure ≥160 mm Hg or diastolic blood pressure ≥100 mm Hg) and NORRISK 2 and the 2017 guidelines (serum total cholesterol ≥7 mmol/L, low density lipoprotein (LDL) cholesterol ≥5 mmol/L, systolic blood pressure ≥160 mm Hg or diastolic blood pressure ≥100 mm Hg). Results The total proportion at high risk as defined by a risk score was 12.0% using NORRISK 1 and 9.8% using NORRISK 2. When including single risk factors specified by the guidelines, the total proportion eligible for intervention was 15.5% using NORRISK 1 and the 2009 guidelines and 18.9% using NORRISK 2 and the 2017 guidelines. The lowered threshold for total cholesterol and specified cut-off for LDL cholesterol stand for a large proportion of the increase in population at risk. Conclusion The population proportion eligible for intervention increased by 3.4 percentage points from 2009 to 2017 using the revised NORRISK 2 score and guidelines. Data may be obtained from a third party and are not publicly available.

中文翻译:


心血管风险评估工具的变化和更新的挪威心血管疾病一级预防指南增加了面临风险的人口比例:2015-2016 年特罗姆瑟研究



目的 使用挪威 NORRISK 1(预测 10 年 CVD 死亡风险)和挪威国家指南(自 2009 年起)与更新的 NORRISK 2(预测 10 年 CVD 死亡风险)比较心血管疾病 (CVD) 高风险人群的比例CVD 的致命和非致命风险以及 2017 年挪威国家指南。方法 我们纳入了来自挪威基于人群的特罗姆瑟研究(2015-2016)的参与者,年龄为 40-69 岁,无 CVD 病史(n=16 566)。符合干预条件的总比例由NORRISK 1和2009年指南(血清总胆固醇≥8 mmol/L,收缩压≥160 mm Hg或舒张压≥100 mm Hg)和NORRISK 2和2017年指南(血清总胆固醇≥8 mmol/L,收缩压≥160 mm Hg)和NORRISK 2和2017年指南确定。总胆固醇≥7 mmol/L,低密度脂蛋白(LDL)胆固醇≥5 mmol/L,收缩压≥160 mm Hg 或舒张压≥100 mm Hg)。结果 使用 NORRISK 1 定义的风险评分定义的高风险总比例为 12.0%,使用 NORRISK 2 为 9.8%。当包括指南指定的单一风险因素时,使用 NORRISK 1 和2009 年指南,18.9% 使用 NORRISK 2 和 2017 年指南。总胆固醇阈值的降低和低密度脂蛋白胆固醇的指定截止值代表了高危人群增加的很大一部分。结论 使用修订后的 NORRISK 2 评分和指南,2009 年至 2017 年,符合干预条件的人口比例增加了 3.4 个百分点。数据可能从第三方获得,并且不公开。
更新日期:2021-08-30
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