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Disputed paternity presumption in Burkina Faso: determination of the biological fathers of children using ABO-rhesus/hemoglobin electrophoresis and STR assays
Journal of Genetic Engineering and Biotechnology Pub Date : 2021-08-30 , DOI: 10.1186/s43141-021-00221-3
Missa Millogo 1, 2 , Serge Theophile Soubeiga 2, 3, 4 , Bapio Valerie Jean Telesphore Bazie 2, 3, 5 , Theodora Mahoukede Zohoncon 2, 3, 6 , Abdoul Karim Ouattara 2, 3 , Albert Theophane Yonli 2, 3 , Jacques Simpore 2, 3, 6
Affiliation  

In resource-limited countries, ABO, HLA, MNS, Kells, and hemoglobin electrophoresis are classic tests for the resolution of paternity disputes due to their affordable cost. The limitations of these tests in cases of disputed paternity require the use of Short Tandem Repeats (STR) for their certification. This study aimed to determine the biological fathers of children using ABO-rhesus/hemoglobin electrophoresis and STR assays in Burkina Faso, West Africa. Of the fourteen trios studied, the ABO-rhesus/hemoglobin electrophoresis analysis revealed ten probable inclusion cases, three exclusion cases, and one undetermined paternity. DNA STR analysis found five inclusions of paternity out of the ten probable inclusions with ABO-rhesus/hemoglobin electrophoresis assay versus nine exclusions of paternity. This study showed that the implementation of the analysis of short tandem repeat is required to resolve increasing disputed filiation cases in Burkina Faso.

中文翻译:

布基纳法索有争议的亲子关系推定:使用 ABO 恒河猴/血红蛋白电泳和 STR 检测确定孩子的亲生父亲

在资源有限的国家,ABO、HLA、MNS、Kells 和血红蛋白电泳由于其成本低廉,是解决亲子纠纷的经典测试。在有争议的亲子关系的情况下,这些测试的局限性要求使用短串联重复 (STR) 进行认证。本研究旨在在西非布基纳法索使用 ABO 恒河猴/血红蛋白电泳和 STR 检测确定儿童的生父。在研究的 14 个三人组中,ABO 恒河猴/血红蛋白电泳分析揭示了 10 个可能的包含病例、3 个排除病例和一个未确定的亲子关系。DNA STR 分析通过 ABO 恒河猴/血红蛋白电泳分析发现 10 个可能的内含物中有 5 个包含亲子关系,而 9 个排除亲子关系。
更新日期:2021-08-30
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