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Disputed paternity presumption in Burkina Faso: determination of the biological fathers of children using ABO-rhesus/hemoglobin electrophoresis and STR assays
Journal of Genetic Engineering and Biotechnology ( IF 3.6 ) Pub Date : 2021-08-30 , DOI: 10.1186/s43141-021-00221-3
Missa Millogo 1, 2 , Serge Theophile Soubeiga 2, 3, 4 , Bapio Valerie Jean Telesphore Bazie 2, 3, 5 , Theodora Mahoukede Zohoncon 2, 3, 6 , Abdoul Karim Ouattara 2, 3 , Albert Theophane Yonli 2, 3 , Jacques Simpore 2, 3, 6
Affiliation  

In resource-limited countries, ABO, HLA, MNS, Kells, and hemoglobin electrophoresis are classic tests for the resolution of paternity disputes due to their affordable cost. The limitations of these tests in cases of disputed paternity require the use of Short Tandem Repeats (STR) for their certification. This study aimed to determine the biological fathers of children using ABO-rhesus/hemoglobin electrophoresis and STR assays in Burkina Faso, West Africa. Of the fourteen trios studied, the ABO-rhesus/hemoglobin electrophoresis analysis revealed ten probable inclusion cases, three exclusion cases, and one undetermined paternity. DNA STR analysis found five inclusions of paternity out of the ten probable inclusions with ABO-rhesus/hemoglobin electrophoresis assay versus nine exclusions of paternity. This study showed that the implementation of the analysis of short tandem repeat is required to resolve increasing disputed filiation cases in Burkina Faso.

中文翻译:


布基纳法索有争议的亲子关系推定:使用 ABO 恒河猴/血红蛋白电泳和 STR 检测确定儿童的亲生父亲



在资源有限的国家,ABO、HLA、MNS、Kells 和血红蛋白电泳因其费用低廉而成为解决亲子纠纷的经典测试。在有争议的亲子关系情况下,这些测试的局限性要求使用短串联重复序列 (STR) 进行认证。本研究旨在利用 ABO 恒河猴/血红蛋白电泳和 STR 检测在西非布基纳法索确定儿童的亲生父亲。在研究的十四个三人组中,ABO-恒河猴/血红蛋白电泳分析显示十个可能的包含案例、三个排除案例和一个未确定的亲子关系。 DNA STR 分析发现,ABO 恒河猴/血红蛋白电泳检测的 10 种可能包含物中,有 5 种是亲子关系,而 9 种是排除亲子关系。这项研究表明,需要实施短串联重复分析来解决布基纳法索日益增加的有争议的亲子关系案件。
更新日期:2021-08-30
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