Porphyromonas gingivalis (P. gingivalis) and Fusobacterium nucleatum (F. nucleatum) participate in the formation and progression of periodontitis. They can exert virulence by invading into host cells, but the interaction between them and their specific mechanisms remain unclear. The purpose of this study was to study the effect of P. gingivalis outer membrane vesicles (OMVs) on the ability of F. nucleatum to invade oral epithelial cells, and the reasons for the influence.

中文翻译：

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牙龈卟啉单胞菌外膜囊泡通过下调FadA和Foma抑制具核梭杆菌侵入口腔上皮细胞

牙龈卟啉单胞菌（P. gingivalis）和具核梭杆菌（F. nucleatum）参与牙周炎的形成和发展。它们可以通过侵入宿主细胞来发挥毒力，但它们之间的相互作用及其具体机制仍不清楚。本研究的目的是研究牙龈卟啉单胞菌外膜囊泡（OMVs）对有核梭菌侵袭口腔上皮细胞能力的影响，以及影响的原因。