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Complete ophthalmoplegia secondary to idiopathic intracranial hypertension managed successfully with dural sinus stenting: A case and systematic review
Clinical Neurology and Neurosurgery ( IF 1.8 ) Pub Date : 2021-08-30 , DOI: 10.1016/j.clineuro.2021.106910
Mansour Mathkour 1 , Tyler Scullen 1 , Mitchell D Kilgore 2 , Edna E Gouveia 3 , Julie Chu 2 , Hussam Abou-Al-Shaar 4 , R Shane Tubbs 1 , Fawad Khan 5 , Cuong J Bui 1
Affiliation  

Idiopathic Intracranial Hypertension (IIH) typically occurs in obese (BMI >30 kg/m2) females of childbearing age in the absence of any apparent intracranial space-occupying lesion. Patients typically present with headache, nausea, vomiting, tinnitus, and blurry vision secondary to increased intracranial pressure, with more severe cases involving cranial neuropathies and ophthalmological manifestations. Complete ophthalmoplegia is a rare event in IIH. In such cases, aggressive management with pharmacological, endovascular, and surgical intervention is essential to hasten recovery and limit long-term neurological and visual deficits. Herein, we present a rare case of a patient with IIH associated with third, fourth, and sixth cranial nerve palsies, resulting in complete unilateral ophthalmoplegia, who underwent dural sinus stenting and 2.5-year follow-up revealed complete resolution with full extraocular movements. We also perform a systematic literature review of complete and partial ophthalmoplegia secondary to IIH, highlighting the associated presentations, pathophysiology, management, and outcomes.



中文翻译:

硬脑膜窦支架置入术成功治疗特发性颅内高压继发的完全性眼肌麻痹:病例和系统评价

特发性颅内高压(IIH)通常发生在没有任何明显颅内占位病变的肥胖(BMI>30 kg/m 2 )育龄女性中。患者通常会因颅内压增高而出现头痛、恶心、呕吐、耳鸣和视力模糊,更严重的病例会出现颅神经病变和眼科表现。完全性眼肌麻痹在 IIH 中是罕见的。在这种情况下,通过药物、血管内和手术干预进行积极的治疗对于加速康复和限制长期神经和视力缺陷至关重要。在此,我们介绍了一名罕见的 IIH 患者,该患者伴有第三、第四和第六脑神经麻痹,导致完全单侧眼肌麻痹,接受硬脑膜窦支架置入术,2.5 年随访显示完全缓解,眼外运动完全。我们还对 IIH 继发的完全性和部分性眼肌麻痹进行了系统的文献综述,重点介绍了相关的表现、病理生理学、治疗和结果。

更新日期:2021-09-21
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