A room-temperature electrochemical strategy for hydrogenation (deuteration) and reverse dehydrogenation of N-heterocycles over a bifunctional MoNi₄ electrode is developed, which includes the hydrogenation of quinoxaline using H₂O as the hydrogen source with 80% Faradaic efficiency and the reverse dehydrogenation of hydrogen-rich 1,2,3,4-tetrahydroquinoxaline with up to 99% yield and selectivity. The in situ generated active hydrogen atom (H*) is plausibly involved in the hydrogenation of quinoxaline, where a consecutive hydrogen radical coupled electron transfer pathway is proposed. Notably, the MoNi₄ alloy exhibits efficient quinoxaline hydrogenation at an overpotential of only 50 mV, owing to its superior water dissociation ability to provide H* in alkaline media. In situ Raman tests indicate that the Ni^II/Ni^III redox couple can promote the dehydrogenation process, representing a promising anodic alternative to low-value oxygen evolution. Impressively, electrocatalytic deuteration is easily achieved with up to 99% deuteration ratios using D₂O. This method is capable of producing a series of functionalized hydrogenated and deuterated quinoxalines.

开发了一种在双功能 MoNi ₄电极上对N-杂环进行加氢（氘化）和反向脱氢的室温电化学策略，其中包括使用 H ₂ O 作为氢源的喹喔啉加氢（法拉第效率为 80%）和反向脱氢富氢 1,2,3,4-四氢喹喔啉的产率和选择性高达 99%。该原位生成的活性氢原子（H *）的振振有词涉及喹喔啉，其中提出了一种连续氢自由基偶联的电子传递路径的氢化。值得注意的是，MoNi ₄合金在仅 50 mV 的过电位下表现出有效的喹喔啉氢化，因为它具有在碱性介质中提供 H* 的优异水离解能力。原位拉曼测试表明，Ni ^II / Ni ^III氧化还原对可以促进脱氢过程，是低值析氧的有前途的阳极替代品。令人印象深刻的是，使用 D ₂ O可以轻松实现高达 99% 的氘化率的电催化氘化。该方法能够生产一系列功能化的氢化和氘化喹喔啉。