Mechanochemical Synthesis of 1,2-Diketoindolizine Derivatives from Indolizines and Epoxides Using Piezoelectric Materials,Organic Letters

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Mechanochemical Synthesis of 1,2-Diketoindolizine Derivatives from Indolizines and Epoxides Using Piezoelectric Materials
Organic Letters ( IF 4.9 ) Pub Date : 2021-08-30 , DOI: 10.1021/acs.orglett.1c02575
Yumei Wang ₁ , Ziwu Zhang ₁ , Lichan Deng ₁ , Tianfeng Lao ₁ , Zhengquan Su ₂ , Yue Yu _{1,

3} , Hua Cao ₁

Affiliation

A simple and efficient mechanochemical-induced approach for the synthesis of 1,2-diketoindolizine derivatives has been developed. BaTiO₃ was used as the piezoelectric material in this transformation. This method features no usage of solvent, simple experimental operation, scalable potential, and high conversion efficiency, which make it attractive and practical.

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