Background

Previous studies have shown improved post-surgical outcomes in patients who travel farther for glioblastoma treatment. This study investigates socioeconomic and facility factors that may influence this relationship.

Methods

Overall survival was calculated and compared by distance to treatment facility using univariate and multivariate survival models. The analysis was stratified by facility type, income quartile and insurance status and the association re-evaluated. Kaplan-Meier survival curves were created to analyze the relationship between overall survival and distance group.

Results

Individuals who traveled less than 5 miles to treatment had the shortest overall survival (11.8 months), while those who traveled greater than 50 miles had the longest survival (12.9 months). Stratification by income quartile failed to demonstrate an association between distance traveled and survival for those making less than $63,000 (adjusted hazard ratio range: 0.94–1.01). There was no association between survival and distance traveled for patients treated at a community cancer center, comprehensive community cancer center or an integrated network cancer program (adjusted hazard ratio range: 0.86–1.04).

Conclusion

Financial strain, rather than distance traveled to treatment, may be associated with glioblastoma survival.

中文翻译：

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胶质母细胞瘤治疗的距离：衡量社会经济地位对生存的影响

背景

先前的研究表明，为胶质母细胞瘤治疗走得更远的患者的术后结果有所改善。本研究调查了可能影响这种关系的社会经济和设施因素。

方法

使用单变量和多变量生存模型，通过与治疗设施的距离计算和比较总生存期。该分析按设施类型、收入四分位数和保险状况进行分层，并重新评估了该协会。创建 Kaplan-Meier 生存曲线以分析总体生存与距离组之间的关系。

结果

距离治疗不到 5 英里的个体总生存期最短（11.8 个月），而距离超过 50 英里的个体生存期最长（12.9 个月）。对于收入低于 63,000 美元的人（调整后的风险比范围：0.94-1.01），按收入四分位数进行的分层未能证明行进距离与生存率之间存在关联。对于在社区癌症中心、综合社区癌症中心或综合网络癌症计划（调整后的风险比范围：0.86-1.04）接受治疗的患者，生存率和旅行距离之间没有关联。

结论

经济压力，而不是治疗的距离，可能与胶质母细胞瘤的存活有关。