Clinical Research in Cardiology ( IF 3.8 ) Pub Date : 2021-08-28 , DOI: 10.1007/s00392-021-01917-9 Patrick Müller 1 , Lars Eckardt 1 , Bob Weijs 2, 3 , Nadine M. A. A. Bemelmans 2 , Harry J. G. M. Crijns 2 , Dominik Linz 2, 4, 5 , Dennis W. den Uijl 2 , Andreas Mügge 6, 7 , Jeroen J. Bax 8
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Atrial fibrillation (AF) is a major cause of cardiovascular morbidity and mortality. To early detect and to avoid AF-related complications, several cardiac imaging modalities and approaches aim to quantify the severity of the underlying atrial cardiomyopathy (i.e., the extent of atrial remodeling). However, most established cardiac imaging modalities just incorporate single components of atrial remodeling and do not reflect the complete multifactorial process, which may contribute to their limited predictive value. Echocardiography-derived PA-TDI duration is a sophisticated echocardiographic parameter to assess total atrial conduction time and directly reflects both electrical and structural changes to the atria. Therefore, PA-TDI duration provides a more comprehensive quantification of the extent of atrial remodeling than other imaging modalities. In this article we review the role of PA-TDI duration as a marker of atrial remodeling and summarize the available data on PA-TDI duration to identify patients at risk for AF, as well as to guide AF management. Moreover, we discuss how to assess PA-TDI duration and provide recommendations on the implementation of PA-TDI duration into routine clinical care.
Graphic abstract
中文翻译：
超声心动图衍生的总心房传导时间（PA-TDI 持续时间）：心房颤动管理中的风险分层和指导
心房颤动 (AF) 是心血管发病率和死亡率的主要原因。为了早期检测和避免 AF 相关并发症，几种心脏成像方式和方法旨在量化潜在心房心肌病的严重程度（即心房重构的程度）。然而，大多数已建立的心脏成像方式仅包含心房重构的单个组成部分，并不能反映完整的多因素过程，这可能导致其预测价值有限。超声心动图衍生的 PA-TDI 持续时间是一个复杂的超声心动图参数，用于评估总心房传导时间，并直接反映心房的电和结构变化。因此，与其他成像方式相比，PA-TDI 持续时间可以更全面地量化心房重构的程度。在本文中，我们回顾了 PA-TDI 持续时间作为心房重构标志物的作用，并总结了 PA-TDI 持续时间的可用数据，以识别有 AF 风险的患者，并指导 AF 管理。此外，我们讨论了如何评估 PA-TDI 持续时间，并就 PA-TDI 持续时间在常规临床护理中的实施提供建议。
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