Exosomes participate in intercellular communication and act as important molecular vehicles in the regulation of numerous physiological and pathological processes, including autoimmune development. The role of circulating exosomes in the development of autoimmune uveitis is unknown. In this study, using the rat model of experimental autoimmune uveitis, which has clinical and histological features of pan uveitis in man, we evaluated the immunoregulatory function of circulating exosomes.

中文翻译：

---

在自身免疫性葡萄膜炎中使用循环外泌体进行疫苗接种可预防复发性眼内炎症

外泌体参与细胞间通讯，并在调节许多生理和病理过程（包括自身免疫发育）中充当重要的分子载体。循环外泌体在自身免疫性葡萄膜炎发展中的作用尚不清楚。在这项研究中，我们使用具有人类全葡萄膜炎临床和组织学特征的实验性自身免疫性葡萄膜炎大鼠模型，评估了循环外泌体的免疫调节功能。