A novel MnCr₂O₄ nanocomposite modified carbon paste electrode (MnCr₂O₄/MCPE) based sensor were developed and validated by electrochemical detection of norepinephrine (NE). The MnCr₂O₄ nanocomposite was synthesized by hydrothermal method. The synthesized nanocomposite was characterized by X-ray diffraction (XRD), scanning electron microscope (SEM) and Infra Red (IR) spectroscopy techniques. To identify the redox properties of the MnCr₂O₄/MCPE were examined by cyclic voltammetry studies. The investigation of modified electrode has high electroactive surface area, the oxidation and reduction peak occurred at pH7.4 the supporting electrolyte was 0.2 M phosphate buffer solution. MnCr₂O₄/MCPE as very low detection limit (LOD) is 0.034 µM, high sensitivity, wide linear range (0.0003 mM to 0.0045 mM), applied to the injection sample analysis and the obtained results are satisfactory, good reproducibility exhibits great potential in practical applications.

开发了一种新型 MnCr ₂ O ₄纳米复合改性碳糊电极 (MnCr ₂ O ₄ /MCPE) 传感器，并通过去甲肾上腺素 (NE) 的电化学检测对其进行了验证。采用水热法合成了MnCr ₂ O ₄纳米复合材料。合成的纳米复合材料通过 X 射线衍射 (XRD)、扫描电子显微镜 (SEM) 和红外 (IR) 光谱技术进行表征。确定 MnCr ₂ O ₄的氧化还原特性/MCPE 通过循环伏安法研究进行检查。改性电极具有较高的电活性表面积，氧化还原峰出现在pH7.4，支持电解质为0.2M磷酸盐缓冲液。MnCr ₂ O ₄ /MCPE作为极低检出限（LOD）为0.034 µM，灵敏度高，线性范围宽（0.0003 mM至0.0045 mM），应用于进样分析，获得的结果令人满意，重现性好，显示出很大的潜力在实际应用中。