Stable Sf9 cell pools as a system for rapid HIV-1 virus-like particle production,Journal of Chemical Technology and Biotechnology

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Stable Sf9 cell pools as a system for rapid HIV-1 virus-like particle production
Journal of Chemical Technology and Biotechnology ( IF 2.8 ) Pub Date : 2021-08-28 , DOI: 10.1002/jctb.6895
Eduard Puente‐Massaguer _{1,

2} , Paula Grau‐Garcia ₁ , Florian Strobl _{3,

4} , Reingard Grabherr ₄ , Gerald Striedner ₄ , Martí Lecina ₅ , Francesc Gòdia ₁

Affiliation

The emergence of infectious diseases is accelerating the intensification of bioprocess strategies to support the increasing demand for the manufacture of higher quantities of vaccines in short timeframes. Here, the development of stable Sf9 cell pools producing human immunodeficiency virus serotype 1 (HIV-1) Gag-eGFP virus-like particles (VLPs) is assessed.

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