Dielectrophoresis is a well-understood phenomenon that has been widely utilized in biomedical applications. Recent advancements in miniaturization have contributed to the development of dielectrophoretic-based devices for a wide variety of biomedical applications. In particular, the integration of dielectrophoresis with microfluidics, fluorescence, and electrical impedance has produced devices and techniques that are attractive for screening and diagnosing diseases. This review article summarizes the recent utility of dielectrophoresis in assays of biomarker detection. Common screening and diagnostic biomarkers, such as cellular, protein, and nucleic acid, are discussed. Finally, the potential use of recent developments in machine learning approaches toward improving biomarker detection performance is discussed. This review article will be useful for researchers interested in the recent utility of dielectrophoresis in the detection of biomarkers and for those developing new devices to address current gaps in dielectrophoretic biomarker detection.

中文翻译：

---

介电泳对生物标志物检测的最新进展：2014 年至 2021 年间发表的研究总结

介电泳是一种广为人知的现象，已广泛应用于生物医学应用中。小型化的最新进展有助于开发用于各种生物医学应用的基于介电泳的设备。特别是，介电泳与微流体、荧光和电阻抗的结合产生了对筛查和诊断疾病具有吸引力的设备和技术。这篇综述文章总结了介电泳在生物标志物检测分析中的最新应用。讨论了常见的筛查和诊断生物标志物，例如细胞、蛋白质和核酸。最后，讨论了机器学习方法的最新发展在提高生物标志物检测性能方面的潜在用途。