Narrow-band imaging (NBI) highlights the surface structures and vessels of colorectal polyps and is useful for determining the polyp histology. The narrow-band imaging international colorectal endoscopic (NICE) classification is a diagnostic tool for determining colorectal polyp histology based on NBI without optical magnification. In this study, we aimed to investigate the value of each type of the NICE classification for determining colorectal polyp histology using endoscopy data accumulated in a clinical setting. Endoscopy data for 534 colorectal polyps (316 patients) treated at our facility were retrospectively analyzed. First, we investigated the diagnostic performance of each type of the NICE classification for the optical diagnosis of colorectal polyp histology. The procedures were performed by experienced endoscopists using high-definition colonoscopy without optical magnification. Second, inter-observer and intra-observer agreements were assessed after providing experts and non-experts with a short lecture on the NICE classification. Using 50 fine NBI images of colorectal polyps without optical magnification, the inter-observer and intra-observer agreements between five experts and five non-experts were assessed. The sensitivity, specificity, and accuracy values were 86.0%, 99.6%, and 98.5% for NICE type 1 lesions; 99.2%, 85.2%, and 97.8% for NICE type 2 lesions; and 81.8%, 99.6%, and 99.3% for NICE type 3 lesions, respectively. The inter-observer and intra-observer agreements ranged from substantial to excellent for both experts and non-experts. The NICE classification had good diagnostic ability in terms of determining the polyp histology and demonstrated a high level of reproducibility among experts and non-experts. Thus, the NICE classification is a useful clinical tool that can be used without optical magnification.

中文翻译：

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窄带成像国际结直肠内镜分类在临床实践中对结直肠息肉组织学光学诊断的应用：回顾性研究

窄带成像 (NBI) 突出显示结直肠息肉的表面结构和血管，可用于确定息肉组织学。窄带成像国际结直肠内镜（NICE）分类是一种基于NBI确定结直肠息肉组织学的诊断工具，无需光学放大。在本研究中，我们旨在使用临床环境中积累的内窥镜数据来研究每种 NICE 分类在确定结直肠息肉组织学方面的价值。回顾性分析了在我们机构治疗的 534 例结直肠息肉（316 例患者）的内窥镜检查数据。首先，我们研究了每种 NICE 分类对结直肠息肉组织学光学诊断的诊断性能。该程序由经验丰富的内窥镜医师使用高清晰度结肠镜进行，无需光学放大。其次，在为专家和非专家提供关于 NICE 分类的简短讲座后，对观察者间和观察者内的协议进行了评估。使用 50 幅未经光学放大的结直肠息肉的精细 NBI 图像，评估了五名专家和五名非专家之间的观察者间和观察者内的协议。NICE 1 型病变的敏感性、特异性和准确性值分别为 86.0%、99.6% 和 98.5%；NICE 2 型病变分别为 99.2%、85.2% 和 97.8%；NICE 3 型病变分别为 81.8%、99.6% 和 99.3%。对于专家和非专家而言，观察者间和观察者内的协议从实质性到优秀不等。NICE 分类在确定息肉组织学方面具有良好的诊断能力，并且在专家和非专家之间表现出高度的可重复性。因此，NICE 分类是一种有用的临床工具，无需光学放大即可使用。