Aims. The prevalence of CKD in patients with diabetes mellitus in the Middle East region is unknown. Therefore, we aimed to understand the pooled prevalence of CKD in patients with diabetes mellitus in the Middle East region. Methods. PubMed, Embase, and Cochrane databases were searched for relevant studies up to October 2020. The search strategy was conducted using both keywords and MeSH terms. Randomised controlled trials (RCTs) and observational studies that included patients from all age groups and any study design that reported on the prevalence of CKD in patients with diabetes mellitus were included. The pooled estimate for the prevalence of CKD in patients with diabetes was calculated using random-effect models with 95% confidence intervals (CIs). Results. A total of 489 citations were identified, of which only nine studies matched our inclusion criteria and were included in the meta-analysis. All of the studies used an observational study design covering a total of 59,395 patients with type 2 diabetes mellitus. The pooled estimate of the prevalence of CKD in patients with diabetes mellitus was 28.96% (95% CI: 19.80–38.11). Conclusions. A high prevalence of CKD in patients with diabetes mellitus in the Middle East region was found. Further epidemiological studies are warranted in this area to have a better estimate of the prevalence of CKD among DM in the Middle East region.

中文翻译：

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中东糖尿病患者慢性肾脏病的患病率：系统回顾和荟萃分析


目标。中东地区糖尿病患者中 CKD 的患病率尚不清楚。因此，我们旨在了解中东地区糖尿病患者 CKD 的汇总患病率。方法。在 PubMed、Embase 和 Cochrane 数据库中检索了截至 2020 年 10 月的相关研究。检索策略是使用关键词和 MeSH 术语进行的。纳入所有年龄组患者的随机对照试验 (RCT) 和观察性研究以及报告糖尿病患者 CKD 患病率的任何研究设计。使用具有 95% 置信区间 (CI) 的随机效应模型计算糖尿病患者 CKD 患病率的汇总估计值。结果。总共确定了 489 条引用，其中只有 9 项研究符合我们的纳入标准并纳入荟萃分析。所有研究均采用观察性研究设计，涵盖总共 59,395 名 2 型糖尿病患者。糖尿病患者 CKD 患病率的汇总估计值为 28.96%（95% CI：19.80-38.11）。结论。研究发现，中东地区糖尿病患者的 CKD 患病率很高。该领域需要进一步的流行病学研究，以便更好地估计中东地区 DM 中 CKD 的患病率。