Intracerebral hemorrhage (ICH) causes neurotransmitter release, oligemia, membrane depolarization, mitochondrial dysfunction, and results in the high rate of mortality and functional disability. Here, we focus on PTEN-induced kinase 1 (PINK1), a mitochondrial-targeted protein kinase, and explore its role in ICH progression.

中文翻译：

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PINK1通过促进线粒体自噬拮抗脑出血

脑出血 (ICH) 会导致神经递质释放、寡血症、膜去极化、线粒体功能障碍，并导致高死亡率和功能障碍。在这里，我们专注于 PTEN 诱导的激酶 1 (PINK1)，一种线粒体靶向蛋白激酶，并探讨其在 ICH 进展中的作用。