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Resistance exercise intervention on muscular strength and power, and functional capacity in acute hospitalized older adults: a systematic review and meta-analysis of 2498 patients in 7 randomized clinical trials
GeroScience ( IF 5.6 ) Pub Date : 2021-08-28 , DOI: 10.1007/s11357-021-00446-7
Marcelo A S Carneiro 1, 2 , Cristiane M C Franco 3 , Alan L Silva 1 , Pâmela Castro-E-Souza 1 , Gabriel Kunevaliki 1 , Mikel Izquierdo 4, 5 , Edilson S Cyrino 1 , Camila S Padilha 6
Affiliation  

Abstract

To date, no meta-analytical study evaluating the benefits of resistance exercise intervention on muscular strength and power and functional capacity in acute hospitalized older adults was conducted. Then, to synthesize the emerging evidence on the effects of resistance exercise intervention on muscular strength and power and functional capacity in acute hospitalized older adults, two independent authors performed a systematic search (PubMed, Scopus, Web of Science, and SciELO) until January 2021. Randomized clinical trials were included regarding the effects of resistance exercise and hospital usual care. The Cochrane Collaboration assessment tool was used to analyze the risk of bias. The comparisons included muscular strength (isometric handgrip strength and one-repetition maximum test of leg press), muscular power (output during leg press exercise), and functional capacity (timed-up-and-go, and short physical performance battery). Resistance exercise intervention increased muscular strength (isometric handgrip strength: mean difference = 2.50 kg, 95% confidence interval (CI) = 1.33, 3.67; and one-repetition maximum test of leg press: mean difference = 19.28 kg, 95% confidence interval = 14.70, 23.86) and muscular power (mean difference = 29.52 W, 95% confidence interval = 28.84, 30.21), and functional capacity (timed-up-and-go: mean difference = 3.40 s, 95% confidence interval = 0.47, 6.36; and short physical performance battery: mean difference = 1.29 points, 95% confidence interval = 0.10, 2.48) at discharge compared with hospital usual care. This meta-analysis endorses the increase of muscular strength and power gains and improving the functional capacity in favor of resistance exercise intervention in acute hospitalized older adults.

Trial Registration

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020203658



中文翻译:

抗阻运动干预对急性住院老年人肌肉力量和功能能力的影响:对 7 项随机临床试验中 2498 名患者的系统评价和荟萃分析

摘要

迄今为止,尚未进行荟萃分析研究评估阻力运动干预对急性住院老年人肌肉力量和力量和功能能力的益处。然后,为了综合新出现的关于阻力运动干预对急性住院老年人肌肉力量和力量以及功能能力影响的证据,两位独立作者进行了系统搜索(PubMed、Scopus、Web of Science 和 SciELO),直到 2021 年 1 月. 随机临床试验包括关于抗阻运动和医院常规护理的影响。Cochrane Collaboration 评估工具用于分析偏倚风险。比较包括肌肉力量(等长握力和一次重复最大腿部压力测试),肌肉力量(腿部推举运动期间的输出)和功能能力(定时启动和短的身体表现电池)。阻力运动干预增加了肌肉力量(等长握力:平均差 = 2.50 公斤,95% 置信区间 (CI) = 1.33, 3.67;和一次重复最大腿部推举测试:平均差 = 19.28 公斤,95% 置信区间 = 14.70, 23.86) 和肌肉力量 (平均差 = 29.52 W, 95% 置信区间 = 28.84, 30.21), 和功能能力 (timed-up-and-go: 平均差 = 3.40 s, 95% 置信区间 = 0.47, 6.36 ; 和短期身体表现电池组:出院时与医院常规护理相比,平均差异 = 1.29 分,95% 置信区间 = 0.10, 2.48)。

试用注册

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020203658

更新日期:2021-08-29
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