PURPOSE Obesity is prevalent in gynecological cancer survivors and is associated with impaired health outcomes. Concerns due to cancer and its treatment may impact changes in lifestyle after cancer. This study aimed to assess the association between cancer-related psychosocial factors and changes in physical activity and diet, 18 months after initial treatment among gynecological cancer survivors. METHODS Cross-sectional data from the ROGY Care study were used, including endometrial and ovarian cancer patients treated with curative intent. The Impact of Cancer Scale (IOCv2) was used to assess cancer-related psychosocial factors. Self-reported changes in nutrients/food groups and in physical activity post-diagnosis were classified into change groups (less/equal/more). Multivariable logistic regression models were used to assess associations. RESULTS Data from 229 cancer survivors (59% endometrial, 41% ovarian, mean age 66 ± 9.5, 70% tumor stage I) were analyzed. In total, 20% reported to eat healthier from diagnosis up to 18 months after initial treatment, 17% reported less physical activity and 20% more physical activity. Health awareness (OR 2.79, 95% CI: 1.38; 5.65), body change concerns (OR 3.04 95% CI: 1.71; 5.39), life interferences (OR 4.88 95% 2.29; 10.38) and worry (OR 2.62, 95% CI: 1.42; 4.85) were significantly associated with less physical activity up to 18 months after initial treatment whereby gastrointestinal symptoms were an important confounder. CONCLUSION(S) This study underlines the need to raise awareness of the benefits of a healthy lifestyle and to provide tailored lifestyle advice, taking into account survivors' health awareness, body change concerns, life interferences, worry and gastrointestinal symptoms, in order to improve health behavior among gynecological cancer survivors. TRIAL REGISTRATION http://clinicaltrials.gov Identifier: NCT01185626, August 20, 2010.

中文翻译：

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妇科癌症幸存者中与癌症相关的心理社会因素和自我报告的生活方式变化：PROFILES 注册数据的横断面分析。


目的 肥胖在妇科癌症幸存者中普遍存在，并且与健康结果受损相关。对癌症及其治疗的担忧可能会影响癌症后生活方式的改变。本研究旨在评估妇科癌症幸存者初次治疗 18 个月后癌症相关心理社会因素与体力活动和饮食变化之间的关联。方法 使用 ROGY Care 研究的横断面数据，包括接受治疗的子宫内膜癌和卵巢癌患者。癌症影响量表（IOCv2）用于评估与癌症相关的心理社会因素。自我报告的营养/食物组和诊断后体力活动的变化被分为变化组（更少/等于/更多）。使用多变量逻辑回归模型来评估关联性。结果 分析了 229 名癌症幸存者（59% 为子宫内膜癌，41% 为卵巢癌，平均年龄 66 ± 9.5，70% 肿瘤为 I 期）的数据。总体而言，20% 的人表示从诊断到初始治疗后 18 个月内饮食更加健康，17% 的人表示体力活动减少，20% 的人体力活动增加。健康意识（OR 2.79，95% CI：1.38；5.65）、身体变化担忧（OR 3.04 95% CI：1.71；5.39）、生活干扰（OR 4.88 95% CI：2.29；10.38）和担忧（OR 2.62，95% CI） ：1.42；4.85）与初始治疗后 18 个月内体力活动减少显着相关，其中胃肠道症状是一个重要的混杂因素。 结论 本研究强调需要提高对健康生活方式益处的认识，并考虑幸存者的健康意识、身体变化问题、生活干扰、担忧和胃肠道症状，提供量身定制的生活方式建议，以改善妇科癌症幸存者的健康行为。试验注册 http://clinicaltrials.gov 标识符：NCT01185626，2010 年 8 月 20 日。