Is Galactose a Hormetic Sugar? An Exploratory Study of the Rat Hippocampal Redox Regulatory Network,Molecular Nutrition & Food Research

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Is Galactose a Hormetic Sugar? An Exploratory Study of the Rat Hippocampal Redox Regulatory Network
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2021-08-27 , DOI: 10.1002/mnfr.202100400
Jan Homolak _{1,

2} , Ana Babic Perhoc _{1,

2} , Ana Knezovic _{1,

2} , Ivan Kodvanj _{1,

2} , Davor Virag _{1,

2} , Jelena Osmanovic Barilar _{1,

2} , Peter Riederer _{3,

4} , Melita Salkovic-Petrisic _{1,

2}

Affiliation

Galactose, a ubiquitous monosaccharide with incompletely understood physiology is often exploited for inducing oxidative-stress mediated aging in animals. Recent research demonstrates that galactose can conserve cellular function during periods of starvation and prevent/alleviate cognitive deficits in a rat model of sporadic Alzheimer's disease. The present aim is to examine the acute effects of oral galactose on the redox regulatory network (RRN).

中文翻译：

半乳糖是一种激素糖吗？大鼠海马氧化还原调控网络的探索性研究

半乳糖是一种普遍存在的单糖，其生理学尚不完全清楚，通常被用于诱导动物氧化应激介导的衰老。最近的研究表明，半乳糖可以在饥饿期间保护细胞功能，并预防/减轻散发性阿尔茨海默病大鼠模型中的认知缺陷。目前的目的是检查口服半乳糖对氧化还原调节网络 (RRN) 的急性影响。

更新日期：2021-11-04

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