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Carbapenem-Resistant Enterobacterales Infection After Massive Blast Injury: Use of Cefiderocol Based Combination Therapy
Military Medicine ( IF 1.2 ) Pub Date : 2021-08-28 , DOI: 10.1093/milmed/usab350
B W Carney 1 , J A Rizzo 2, 3 , J F Alderete 1 , R Cindass 2 , A E Markelz 1 , L C Cancio 1
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A military soldier sustained a blast injury in Afghanistan, resulting in amputations and hemipelvectomy. He developed New Delhi metallo-beta-lactamase-producing E. coli bacteremia, soft-tissue infection, and sacral osteomyelitis. These organisms are being increasingly discovered in different communities around the world. He was successfully treated with tigecycline and cefiderocol. Cefiderocol is a novel siderophore-based cephalosporine developed to treat serious infections, including those caused by carbapenem-resistant Enterobacterales.

中文翻译:


大规模爆炸伤后的碳青霉烯类耐药肠杆菌感染:使用头孢地洛联合治疗



一名军人在阿富汗爆炸受伤,导致截肢和半骨盆切除术。他患上了新德里产金属β内酰胺酶大肠杆菌菌血症、软组织感染和骶骨骨髓炎。这些生物体越来越多地在世界各地的不同社区中被发现。替加环素和头孢地考成功治疗了他。头孢菌素是一种新型的基于铁载体的头孢菌素,用于治疗严重感染,包括由耐碳青霉烯类肠杆菌引起的感染。
更新日期:2021-08-28
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