Obesity is a real public health problem and is of growing concern. People are resorting to surgical or endoscopic means to fight against overweight and obesity. In recent years, there has been a marked increase in the use of these means and in particular the insertion of a gastric balloon which seems to present less risk than surgical methods. Renal complications from intragastric balloon placement are extremely rare. We report here the case of compression of the left renal vein revealed by lumbar pain and hematuria in an overweight 39-year-old woman who benefited from the balloon gastric placement one month before symptoms. The scanner made the diagnosis and showed a good evolution after the withdrawal of the balloon. This was a prespecified and retrospective analysis of all consecutive patients who underwent FFR assessment for intermediate coronary lesions between January 2014 and December 2015. The primary endpoint was defined as the 1-year composite of cardiac death, vessel-related myocardial infarction, and clinically-driven target vessel revascularization. In 1554 lesions (23% in women), FFR was lower in men [0.83 ±0.09 vs 0.85 ±0.08, = .004] driven by LAD values (for LAD < .001, LCx or RCA > .40). In proximal lesions (PLs), FFR was lower in men [0.83 ±0.10 vs 0.85 ±0.08, = .004] with comparable values in non-PLs [0.84 ±0.09 vs 0.85 ±0.08, = .36]. In PLs, the primary endpoint was higher in women [HR 3.18 (1.08-9.37), = .035] with comparable outcomes in non-PLs ( = .032 for interaction). In deferred lesions, the primary endpoint was higher in women [HR 2.73 (1.10-6.74), = .03] with no differences in revascularized lesions across sex ( = .02 for interaction). Results were consistent when using propensity score matching analysis. There is a sex-based difference in FFR, particularly in stenoses subtending large myocardium, and more evident in deferred lesions.

中文翻译：

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血流储备分数的性别差异及其对临床结果的影响

肥胖是一个真正的公共卫生问题，并且越来越受到关注。人们正在诉诸手术或内窥镜手段来对抗超重和肥胖。近年来，这些方法的使用显着增加，特别是插入胃气球，这似乎比手术方法的风险更小。胃内气球放置引起的肾脏并发症极为罕见。我们在这里报道了一名超重的 39 岁女性，因腰部疼痛和血尿而发现左肾静脉受压的病例，她在症状出现前一个月接受了胃气球植入术，受益匪浅。扫描仪做出了诊断，并在气球撤回后显示出良好的演变。这是对 2014 年 1 月至 2015 年 12 月期间接受中间冠状动脉病变 FFR 评估的所有连续患者进行的预先设定和回顾性分析。主要终点定义为心源性死亡、血管相关心肌梗死和临床症状的 1 年复合终点。驱动靶血管血运重建。在 1554 个病变中（23% 为女性），男性 FFR 较低 [0.83 ±0.09 vs 0.85 ±0.08, = .004]，受 LAD 值驱动（LAD < .001，LCx 或 RCA > .40）。在近端病变 (PL) 中，男性的 FFR 较低 [0.83 ±0.10 vs 0.85 ±0.08, = .004]，而非 PL 中的 FFR 值相当 [0.84 ±0.09 vs 0.85 ±0.08, = .36]。在 PL 中，女性的主要终点较高 [HR 3.18 (1.08-9.37), = .035]，非 PL 中的结果具有可比性（交互作用 = .032）。在延迟病变中，女性的主要终点较高 [HR 2.73 (1.10-6.74), = .03]，不同性别的血运重建病变没有差异（交互作用 = .02）。使用倾向评分匹配分析时，结果是一致的。 FFR 存在基于性别的差异，特别是在大心肌周围的狭窄中，并且在延迟病变中更明显。