Highly expressed of SERPINA3 indicated poor prognosis and involved in immune suppression in glioma,Immunity, Inflammation and Disease

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Highly expressed of SERPINA3 indicated poor prognosis and involved in immune suppression in glioma
Immunity, Inflammation and Disease ( IF 3.1 ) Pub Date : 2021-08-27 , DOI: 10.1002/iid3.515
Qing Yuan _{1,

2} , Song-Quan Wang _{1,

2} , Guang-Tao Zhang _{1,

2} , Jie He _{1,

2} , Zhi-Dan Liu _{1,

2} , Ming-Rong Wang ₂ , Hong-Qing Cai _{1,

2} , Jing-Hai Wan ₁

Affiliation

The prognosis of patients with glioma is dismal. It has been reported that Serpin peptidase inhibitor clade A member 3 (SERPINA3) is associated with the mobility and invasion of tumor cells. Our study was designed to explore the value of SERPINA3 messenger RNA (mRNA) expression in the biological process, prognosis, and immune significance in glioma.

中文翻译：

SERPINA3的高表达表明预后不良并参与胶质瘤的免疫抑制

胶质瘤患者的预后很差。据报道，Serpin 肽酶抑制剂进化枝 A 成员 3 (SERPINA3) 与肿瘤细胞的迁移和侵袭有关。我们的研究旨在探讨SERPINA3信使 RNA (mRNA) 表达在胶质瘤的生物学过程、预后和免疫意义中的价值。

更新日期：2021-08-27

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