Many aspects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease, COVID-19, have been studied to determine its properties, transmission mechanisms, and pathology. These efforts are aimed at identifying potential approaches to control or treat the disease. Early treatment of novel SARS-CoV-2 infection to minimize symptom progression has minimal evidence; however, many researchers and firms are working on vaccines, and only a few vaccines exist. COVID-19 is affected by several heavy metals and their nanoparticles. We investigated the effects of heavy metals and heavy metal nanoparticles on SARS-CoV-2 and their roles in COVID-19 pathogenesis. AgNPs, AuNPs, gold-silver hybrid NPs, copper nanoparticles, zinc oxide, vanadium, gallium, bismuth, titanium, palladium, silver grafted graphene oxide, and some quantum dots were tested to see if they could minimize the severity or duration of symptoms in patients with SARS-CoV-2 infection when compared to standard therapy.

中文翻译：

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探索重金属及其衍生物对 COVID-19 病理生理学的作用。

对严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 及其疾病 COVID-19 的许多方面进行了研究，以确定其特性、传播机制和病理学。这些努力旨在确定控制或治疗该疾病的潜在方法。早期治疗新型 SARS-CoV-2 感染以尽量减少症状进展的证据很少；然而，许多研究人员和公司都在研究疫苗，但只有少数几种疫苗存在。COVID-19 受到多种重金属及其纳米粒子的影响。我们研究了重金属和重金属纳米粒子对 SARS-CoV-2 的影响及其在 COVID-19 发病机制中的作用。AgNPs、AuNPs、金银杂化 NPs、铜纳米粒子、氧化锌、钒、镓、铋、钛、钯、银接枝氧化石墨烯、