Paramagnetic complexes containing nitric oxide (NO) have been assayed in rat heart and liver tissues by EPR spectroscopy to investigate the time variation of NO production during postnatal development. Nitric oxide levels have been assessed from the intensity of a characteristic EPR signal belonging to the (DETC)₂–Fe²⁺–NO complex. The results show that the content of NO in liver tissues increases within the age interval from 28 to 56 days but does not change significantly in postadolescence. In heart tissues, the nitric oxide level increases in adulthood compared to puberty. The NO level in the rat liver is significantly higher than in heart tissues in all studied age groups.

已通过 EPR 光谱法在大鼠心脏和肝脏组织中测定了含有一氧化氮 (NO) 的顺磁性复合物，以研究出生后发育过程中 NO 产生的时间变化。已从属于 (DETC) ₂ –Fe ²⁺ –NO 复合物的特征 EPR 信号的强度评估一氧化氮水平。结果表明，肝组织中NO含量在28-56天的年龄区间内增加，但在青春期后变化不显着。在心脏组织中，与青春期相比，成年期的一氧化氮水平会增加。在所有研究年龄组中，大鼠肝脏中的 NO 水平显着高于心脏组织。