Magnesium (Mg) alloys can be regarded as the most promising biodegradable implant materials for orthopedic and stent applications due to their good biocompatibility and low Young's modulus which is near to that of natural bone. However, its applicability is hindered because it exhibits a high corrosion rate in the physiological environments. In this work, we fabricated Mg₆₆Zn₃₀Ca₄/Fe bulk metallic glass composites via spark plasma sintering (SPS). We studied the influence of different contents of Fe on the properties of the composites. The results indicated that Fe was uniformly distributed on the surface of Mg₆₆Zn₃₀Ca₄ metallic glass (MG) as a second phase, which led to an improvement in the corrosion resistance and mechanical strength. The standard potential of Mg₆₆Zn₃₀Ca₄/Fe bulk metallic glass (BMG) composites increased as compared to Mg₆₆Zn₃₀Ca₄, while their mechanical strength improved from 355 MPa to 616 MPa. Furthermore, cytotoxicity was investigated via the CCK-8 assay and calcein-AM staining, which revealed that the extraction mediums diluted 6 times (EM × 6) of the Mg₆₆Zn₃₀Ca₄ and Mg₆₆Zn₃₀Ca₄/Fe did not cause cell toxicity on day 3 and 5, while the EM × 6 of the Mg₆₆Zn₃₀Ca₄ showed cytotoxicity on day 1, 3 and 5. Thus, Mg₆₆Zn₃₀Ca₄/Fe BMG composites exhibit significant potential for fabricating implants with good mechanical strength and corrosion resistance.

镁（Mg）合金由于其良好的生物相容性和接近天然骨的低杨氏模量，被认为是最有前途的骨科和支架应用的可生物降解植入材料。然而，它的适用性受到阻碍，因为它在生理环境中表现出很高的腐蚀速率。在这项工作中，我们通过放电等离子烧结 (SPS)制造了 Mg ₆₆ Zn ₃₀ Ca ₄ /Fe 块状金属玻璃复合材料。我们研究了不同Fe含量对复合材料性能的影响。结果表明，Fe在Mg ₆₆ Zn ₃₀ Ca ₄表面均匀分布金属玻璃（MG）作为第二相，从而提高了耐腐蚀性和机械强度。镁的标准电势₆₆的Zn ₃₀的Ca ₄ / Fe的块状金属玻璃（BMG）复合材料相比增加Mg作为₆₆锌₃₀的Ca ₄，而其机械强度从355兆帕提高到616兆帕。此外，通过 CCK-8 测定和钙黄绿素-AM 染色研究了细胞毒性，结果表明提取介质稀释了 Mg ₆₆ Zn ₃₀ Ca ₄和 Mg ₆₆ Zn ₃₀ Ca _{4 的}6 倍（EM × 6）/Fe 在第 3 天和第 5 天没有引起细胞毒性，而 Mg ₆₆ Zn ₃₀ Ca ₄的 EM × 6 在第 1、3 和 5 天显示出细胞毒性。因此，Mg ₆₆ Zn ₃₀ Ca ₄ /Fe BMG 复合材料表现出显着的细胞毒性制造具有良好机械强度和耐腐蚀性的植入物的潜力。