To overcome the problems of refractive index matching and increased disorder when working with traditional heterostructure colloidal photonic crystals (CPCs) with dual or multiple photonic bandgaps (PBGs) for fluorescence enhancement in water, we propose the use of a chemical heterostructure in hollow sphere CPCs (HSCPCs). A partial chemical modification of the HSCPC creates a large contrast in wettability to induce the heterostructure, while the hollow spheres increase the refractive index difference when used in aqueous environment. With the platform, fluorescence enhancement reaches around 160 times in solution, and 72 times (signal-to-background ratio ∼7 times) in cells during proof-of-concept live cardiomyocyte contractility experiments. Such photonic platform can be further exploited for chemical sensing, bioassays, and environmental monitoring. Moreover, the introduction of chemical heterostructures provides new design principles for functionalized photonic devices.

为了克服使用具有双或多光子带隙 (PBG) 的传统异质结构胶体光子晶体 (CPC) 在水中增强荧光时折射率匹配和无序增加的问题，我们建议在空心球 CPC 中使用化学异质结构。 HSCPC)。HSCPC 的部分化学改性在润湿性上产生了很大的反差，以诱导异质结构，而在水性环境中使用时，空心球会增加折射率差异。使用该平台，在概念验证活心肌细胞收缩力实验中，荧光增强在溶液中达到约 160 倍，在细胞中达到 72 倍（信号背景比 ~7 倍）。这种光子平台可以进一步用于化学传感、生物测定、和环境监测。此外，化学异质结构的引入为功能化光子器件提供了新的设计原则。