Light chain deposition disease (LCDD) is a rare entity that is generally discovered in the setting of solid organ dysfunction. The monoclonal gammopathy leads to abnormal deposition of light chains in tissues, most often manifested by way of renal dysfunction. Other organ systems may also be affected, the liver being the second-most common after the kidneys. Liver involvement rarely leads to clinically significant disease, with few case reports in the literature. We present the case of a patient referred to a hepatology clinic for the evaluation of new-onset ascites resulting from portal hypertension secondary to LCDD involving the liver.

中文翻译：

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轻链沉积病：门静脉高压症的一个不寻常的原因

轻链沉积病 (LCDD) 是一种罕见的疾病，通常在实体器官功能障碍的情况下被发现。单克隆丙种球蛋白病导致组织中轻链异常沉积，最常表现为肾功能障碍。其他器官系统也可能受到影响，肝脏是仅次于肾脏的第二常见器官。肝脏受累很少导致有临床意义的疾病，文献中的病例报告很少。我们介绍了一名转诊至肝病门诊的患者，以评估继发于肝脏的 LCDD 门静脉高压引起的新发腹水。