Skeletal muscle tissue engineering (SMTE) is of great significance in the study of skeletal muscle physiology and pathology, which could be used in skeletal muscle graft. The scientometric analysis of SMTE can help researchers to quickly understand the evolutive history, status, novelties, and trend of this field. In this study, we performed a scientometric study that can be used to construct and visualize networks of SMTE using VOSviewer. A total of 1384 documents published between 1994 and 2020 were retrieved and analyzed. Our results showed that number of publications in SMTE has increased slowly from 1994 to 2014 and has increased rapidly from 2015 to 2020. The geographical distribution of publications in terms of total publications about SMTE is concentrated in Europe and the United States. The most productive institution was University of Michigan, while Harvard University and the University of Pittsburgh were ranked the second and third places. SMTE influenced a wide spectrum of disciplines, including Biology and Medicine and Physical Sciences. In addition, the research hotspot of SMTE was expanding from seed cells to the combination with advanced strategies (electrostatic spinning, bioprinting, and materials) for emulating the highly bionic engineered skeletal muscle tissues. This study provided a unique perspective for understanding the history and trends of SMTE, which could help to promote the rapid development of the field.

中文翻译：

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骨骼肌组织工程的全球进化：科学计量学研究

骨骼肌组织工程（SMTE）在骨骼肌生理和病理研究中具有重要意义，可用于骨骼肌移植。SMTE的科学计量分析可以帮助研究人员快速了解该领域的发展历史、现状、新奇和趋势。在这项研究中，我们进行了一项科学计量研究，该研究可用于使用 VOSviewer 构建和可视化 SMTE 网络。共检索和分析了 1994 年至 2020 年间发表的 1384 份文件。我们的研究结果表明，SMTE 的出版物数量从 1994 年到 2014 年增长缓慢，从 2015 年到 2020 年增长迅速。就 SMTE 出版物总量而言，出版物的地理分布集中在欧洲和美国。生产力最高的机构是密歇根大学，而哈佛大学和匹兹堡大学分列第二和第三位。SMTE 影响了广泛的学科，包括生物学、医学和物理科学。此外，SMTE的研究热点正在从种子细胞扩展到与先进策略（静电纺丝、生物打印和材料）的结合，以模拟高度仿生工程骨骼肌组织。本研究为了解SMTE的历史和趋势提供了独特的视角，有助于推动该领域的快速发展。