Dengue fever is one of the most common diseases in tropical and sub-tropical regions of the world, and has a variety of unpleasant and painful symptoms, including fever, bleeding, and even death. Thus, effective methods for its early-stage detection and diagnosis are urgently required. Accordingly, the present study proposes a method for detecting dengue virus through an inspection of the anisotropic polarization properties of blood serum samples, as measured using a backscattering polarimetry technique and Mueller matrix imaging method. The feasibility of the proposed approach is demonstrated using 31 real-world blood samples comprising 17 dengue-infected samples and 14 healthy non-dengue samples. It is shown that the values of the diagonal elements of the Mueller matrix for the non-dengue samples are significantly higher than those for the dengue samples. By contrast, the depolarization index of the dengue samples is higher than that of the non-dengue samples. Moreover, among the four Mueller matrix transformation (MMT) parameters considered in the present study (A, B, T and G), three of them (A, B and T) exhibit significant differences between the non-dengue and dengue samples, respectively. Thus, overall, the results indicate that the proposed method has significant potential as a rapid, low-cost, and effective technique for dengue fever diagnosis applications.

登革热是世界热带和亚热带地区最常见的疾病之一，具有多种令人不快和痛苦的症状，包括发烧、出血，甚至死亡。因此，迫切需要对其早期检测和诊断的有效方法。因此，本研究提出了一种通过检查血清样品的各向异性偏振特性来检测登革热病毒的方法，该特性使用反向散射偏振技术和穆勒矩阵成像方法进行测量。使用 31 个真实世界的血液样本证明了所提出方法的可行性，其中包括 17 个登革热感染样本和 14 个健康非登革热样本。结果表明，非登革热样本的穆勒矩阵对角元素的值显着高于登革热样本的值。相比之下，登革热样本的去极化指数高于非登革热样本。此外，在本研究中考虑的四个穆勒矩阵变换（MMT）参数中（A、B、T和G），其中三个（A、B和T）分别在非登革热样本和登革热样本之间表现出显着差异。因此，总的来说，结果表明所提出的方法作为一种快速、低成本和有效的登革热诊断技术具有巨大的潜力。