PURPOSE To evaluate the dose-response relationship for primary bilateral medial rectus resection in children with exotropia, based on outcomes with this procedure. METHODS Dose-response at both distance and near were calculated as prism diopters correction per millimeter (PD/mm) of rectus resection. All surgeries were performed under general anesthesia through a fornix incision, using doubled-armed 6-0 polyglactin sutures. The resection amount ranged from 5 to 8 mm in each eye, according to the surgical dosage based on the largest angle of preoperative deviation. RESULTS The mean surgical dose-response for all procedures was 2.83 ± 1.03 PD/mm of resection at distance and near. The overall success rate was 53% at the final examination after a mean follow-up of 21.9 months. Patients with moderate angles (25 to 45 PD) had a higher success rate than those with 50 PD or greater deviation. CONCLUSIONS Primary bilateral medial rectus resection should be considered as a surgical alternative in childhood exotropia, particularly for moderate and constant deviations. [J Pediatr Ophthalmol Strabismus. 2022;59(1):24-27.].

中文翻译：

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婴儿外斜视原发性双侧内直肌切除的剂量反应。

目的根据该程序的结果评估外斜视儿童原发性双侧内直肌切除术的剂量反应关系。方法 远近剂量反应计算为直肌切除每毫米的棱镜屈光度校正 (PD/mm)。所有手术均在全身麻醉下通过穹窿切口进行，使用双臂 6-0 polyglactin 缝合线。每只眼的切除量为5～8mm，根据术前最大偏斜角的手术剂量而定。结果 所有手术的平均手术剂量反应为远距离和近距离切除的 2.83 ± 1.03 PD/mm。平均随访 21.9 个月后，期末考试总成功率为 53%。中等角度（25 至 45 PD）的患者比 50 PD 或更大偏差的患者的成功率更高。结论 原发性双侧内直肌切除术应被视为儿童外斜视的手术替代方案，特别是对于中度和持续性外斜视。[J 小儿眼科斜视。2022;59(1):24-27.]。