Microbial infections are a general public health problem worldwide, and their resistance to antibiotics has increased rapidly. The prevention of microbial growth on the surface of cotton fabric is essential to control skin-related infections. In this work, we evaluated A.calamus- zinc oxide nanoparticle (AC-ZnONPs) coated cotton fabrics for antibacterial and cytotoxic activities. The formulated AC-ZnONPs were characterized by UV-spectrophotometer, SEM, EDX, FT-IR, and TEM studies. The AC-ZnONPs amalgamation into the cotton fabrics was done by the dipping technique. The antimicrobial activity and cytotoxic activity were executed by standard approaches. The results of UV-spectrophotometer, TEM, and SEM, and EDX proved the formation and existence of AC-ZnONPs on the fabrics' surface. FT-IR results demonstrated the existence of numerous functional groups. AC-ZnONPs efficiently suppressed the growth of the pathogenic microbes with a maximum inhibition at 60 μg of AC-ZnONPs against E.coli and S.aureus. The AC-ZnONPs coated fabrics also prevented microbial growth with maximum inhibition against P.aeruginosa, K.oxytoca, and A.baumanii. In addition, AC-ZnONPs efficiently suppressed the viability of SK-MEL-3 cells. Altogether, our findings disclosed that the AC-ZnONPs coated fabrics displayed excellent antimicrobial activity against the pathogenic microbes and could be utilized in the medical fields in the future.

微生物感染是世界范围内普遍存在的公共卫生问题，其对抗生素的耐药性迅速增加。防止棉织物表面微生物生长对于控制皮肤相关感染至关重要。在这项工作中，我们评估了菖蒲- 氧化锌纳米颗粒 (AC-ZnONPs) 涂层棉织物具有抗菌和细胞毒性活性。配制的 AC-ZnONP 通过紫外分光光度计、SEM、EDX、FT-IR 和 TEM 研究进行表征。AC-ZnONPs 并入棉织物是通过浸渍技术完成的。抗微生物活性和细胞毒活性通过标准方法进行。紫外分光光度计、TEM、SEM 和 EDX 的结果证明了 AC-ZnONPs 在织物表面的形成和存在。FT-IR 结果证明存在许多官能团。AC-ZnONPs有效地抑制病原微生物具有最大抑制的生长在60微克对AC-ZnONPs的大肠杆菌和金黄色葡萄球菌. AC-ZnONPs 涂层织物还可以最大程度地抑制铜绿假单胞菌、催产酸钾和鲍氏不动杆菌的微生物生长。此外，AC-ZnONPs 有效地抑制了 SK-MEL-3 细胞的活力。总之，我们的研究结果表明，AC-ZnONPs 涂层织物对病原微生物显示出优异的抗菌活性，未来可用于医疗领域。