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Knowledge about the characteristics of stroke-like lesions is expandable
Metabolic Brain Disease ( IF 3.2 ) Pub Date : 2021-08-26 , DOI: 10.1007/s11011-021-00831-3
Josef Finsterer 1
Affiliation  

Stroke-like episodes (SLEs) are a common phenotypic feature of various syndromic and non-syndromic mitochondrial disorders (MIDs), particularly of mitochondrial encephalopathy, lactic acidosis, and stroke-like episode syndrome (MELAS). The morphological equivalent of a SLE is the stroke-like lesion (SLE), a dynamic lesion, which initially expands to regress after weeks or months. SLLs present with typical morphological and structural abnormalities on multimodal magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), and FDG-PET. It is crucial to clearly delineate SLLs from ischemic stroke, as treatment and outcome vary significantly between the two.



中文翻译:

关于中风样病变特征的知识是可扩展的

中风样发作 (SLE) 是各种综合征和非综合征线粒体疾病 (MID) 的常见表型特征,特别是线粒体脑病、乳酸性酸中毒和中风样发作综合征 (MELAS)。SLE 的形态学等价物是中风样病变 (SLE),一种动态病变,最初会在数周或数月后扩展至消退。SLL 在多模态磁共振成像 (MRI)、磁共振波谱 (MRS) 和 FDG-PET 上呈现典型的形态和结构异常。明确区分 SLL 与缺血性卒中至关重要,因为两者之间的治疗和结果差异很大。

更新日期:2021-08-26
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