The Dome: a virtual reality apparatus for freely locomoting rodents,Journal of Neuroscience Methods

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The Dome: a virtual reality apparatus for freely locomoting rodents
Journal of Neuroscience Methods ( IF 2.7 ) Pub Date : 2021-08-26 , DOI: 10.1016/j.jneumeth.2021.109336
Manu S Madhav ₁ , Ravikrishnan P Jayakumar ₂ , Shahin G Lashkari ₃ , Francesco Savelli ₄ , Hugh T Blair ₅ , James J Knierim ₆ , Noah J Cowan ₃

Affiliation

Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, USA; Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD, USA; School of Biomedical Engineering, Djawad Mowafaghian Centre for Brain Health, University of British Columbia, BC, Canada.
Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA; Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD, USA; Mechanical Engineering Department, Johns Hopkins University, Baltimore, MD, USA.
Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD, USA; Mechanical Engineering Department, Johns Hopkins University, Baltimore, MD, USA.
Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA; Francesco Savelli is currently affiliated with the Department of Neuroscience, Developmental and Regenerative Biology, The University of Texas at San Antonio, San Antonio, TX, USA.
Department of Psychology, University of California Los Angeles, Los Angeles, CA, USA.
Mind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, USA.

The cognitive map in the hippocampal formation of rodents and other mammals integrates multiple classes of sensory and motor information into a coherent representation of space. Here, we describe the Dome, a virtual reality apparatus for freely locomoting rats, designed to examine the relative contributions of various spatial inputs to an animal’s spatial representation. The Dome was designed to preserve the range of spatial inputs typically available to an animal in free, untethered locomotion while providing the ability to perturb specific sensory cues. We present the design rationale and corresponding specifications of the Dome, along with a variety of engineering and biological analyses to validate the efficacy of the Dome as an experimental tool to examine the interaction between visual information and path integration in place cells in rodents.

中文翻译：

The Dome：一种用于自由移动啮齿动物的虚拟现实设备

啮齿动物和其他哺乳动物海马形成的认知图将多类感觉和运动信息整合到空间的连贯表示中。在这里，我们描述了 Dome，一种用于自由移动大鼠的虚拟现实设备，旨在检查各种空间输入对动物空间表示的相对贡献。Dome 旨在保留动物通常可以在自由、不受束缚的运动中获得的空间输入范围，同时提供扰乱特定感官线索的能力。我们介绍了圆顶的设计原理和相应的规格，

更新日期：2021-08-26

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