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An intimate encounter: DC3s empower anti-tumor CTLs
Cancer Cell ( IF 48.8 ) Pub Date : 2021-08-26 , DOI: 10.1016/j.ccell.2021.08.010 Ana Stojanovic 1 , Adelheid Cerwenka 1
中文翻译:
亲密接触:DC3s 赋予抗肿瘤 CTLs
更新日期:2021-09-13
Cancer Cell ( IF 48.8 ) Pub Date : 2021-08-26 , DOI: 10.1016/j.ccell.2021.08.010 Ana Stojanovic 1 , Adelheid Cerwenka 1
Affiliation
Discrete tissue niches are emerging as essential prerequisites enabling cell communication and function in both homeostasis and disease. In a recent Cell paper, Di Pilato et al. identify a unique dendritic cell-cytotoxic T cell crosstalk within the perivascular space that facilitates T cell survival and proliferation and drives anti-tumor activity.
中文翻译:
亲密接触:DC3s 赋予抗肿瘤 CTLs
离散的组织生态位正在成为使细胞在体内平衡和疾病中交流和发挥功能的必要先决条件。在最近的一篇Cell论文中,Di Pilato 等人。确定血管周围空间内独特的树突状细胞 - 细胞毒性 T 细胞串扰,促进 T 细胞存活和增殖并驱动抗肿瘤活性。