Background: Probiotics can improve immune function leading to the prevention and management of viral infections like SARS-CoV-2 infection (COVID-19 disease).

Methods: We searched PubMed, EMBASE, Google Scholar, Science Direct, Scopus, and Web of Science up to May 2020 to identify interventional & observational studies documenting the effects of probiotics on incidence, severity, duration, and other clinical manifestations of viral infections, especially SARS-CoV-2-induced.

Results: From a total of 91 records, 24 studies were obtained and classified into three domains based on the efficacy of probiotics on 1) shortening the period and severity of infections (n=9), 2) incidence (n=6), and 3) other clinical complications that may be followed by viral disorders (n=9). Identified probiotics have positive effects on the mentioned domains.

Conclusion: Based on the evidence, some probiotic strains may be useful in SARS-CoV-2 infection; randomized trials are needed to show the facts.

背景：益生菌可以改善免疫功能，从而预防和管理病毒感染，如 SARS-CoV-2 感染（COVID-19 疾病）。

方法：我们检索了截至 2020 年 5 月的 PubMed、EMBASE、Google Scholar、Science Direct、Scopus 和 Web of Science，以确定记录益生菌对病毒感染的发病率、严重程度、持续时间和其他临床表现的影响的干预性和观察性研究，尤其是 SARS-CoV-2 诱导的。

结果：从总共 91 条记录中，获得了 24 项研究，并根据益生菌在以下方面的功效分为三个领域：1) 缩短感染的时间和严重程度 (n=9)，2) 发病率 (n=6)，以及3) 其他可能伴随病毒性疾病的临床并发症 (n=9)。已鉴定的益生菌对上述领域具有积极影响。

结论：根据证据，一些益生菌菌株可能对 SARS-CoV-2 感染有用；需要随机试验来证明事实。