Background: Dysbiosis is related to changes in the composition and behaviour of intestinal microbiota, which may contribute to an age-related decline in metabolic and immune system functioning (immune-senescence).

Objective: The microbiota-targeted dietary and probiotic interventions have been shown to favorably affect the host health by an enhancement of antioxidant activity, improving immune homeostasis, suppression of chronic inflammation, regulation of metabolism and prevention of insulin resistance.

Results: In our study, the use of specific probiotics strains improved the serum concentration of glycemic markers, thereby promoting better overall health.

Conclusion: Probiotics may help correct defects in the gut microbial environment improving metabolic parameters, such as blood sugar levels, glycosylated hemoglobin and a decrease in body weight.

背景：生态失调与肠道微生物群的组成和行为的变化有关，这可能导致与年龄相关的代谢和免疫系统功能下降（免疫衰老）。

目的：以微生物群为目标的饮食和益生菌干预已被证明可以通过增强抗氧化活性、改善免疫稳态、抑制慢性炎症、调节代谢和预防胰岛素抵抗来有益地影响宿主健康。

结果：在我们的研究中，特定益生菌菌株的使用提高了血糖标志物的血清浓度，从而促进了更好的整体健康。

结论：益生菌可能有助于纠正肠道微生物环境中的缺陷，改善代谢参数，如血糖水平、糖化血红蛋白和体重减轻。