It is important to measure quality of life (QoL) after traumatic brain injury (TBI), yet limited studies have compared QoL inventories. In 2579 TBI patients, orthopedic trauma controls, and healthy friend control participants, we compared the Quality of Life After Brain Injury-Overall Scale (QOLIBRI-OS), developed for TBI patients, to the Satisfaction with Life Scale (SWLS), an index of generic life satisfaction. We tested the hypothesis that group differences (TBI and orthopedic trauma vs. healthy friend controls) would be larger for the QOLIBRI-OS than the SWLS and that the QOLIBRI-OS would manifest more substantial changes over time in the injured groups, demonstrating more relevance of the QOLIBRI-OS to traumatic injury recovery. (1) We compared the group differences (TBI vs. orthopedic trauma control vs. friend control) in QoL as indexed by the SWLS versus the QOLIBRI-OS and (2) characterized changes across time in these two inventories across 1 year in these three groups. Our secondary objective was to characterize the relationship between TBI severity and QoL. As compared with healthy friend controls, the QOLIBRI reflected greater reductions in QoL than the SWLS for both the TBI group (all time points) and the orthopedic trauma control group (2 weeks and 3 months). The QOLIBRI-OS better captured expected improvements in QoL during the injury recovery course in injured groups than the SWLS, which demonstrated smaller changes over time. TBI severity was not consistently or robustly associated with self-reported QoL. The findings imply that, as compared with the SWLS, the QOLIBRI-OS appears to identify QoL issues more specifically relevant to traumatically injured patients and may be a more appropriate primary QoL outcome measure for research focused on the sequelae of traumatic injuries.

中文翻译：

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比较脑损伤后的生活质量——总体量表和对生活量表的满意度作为创伤性脑损伤研究的结果测量

衡量创伤性脑损伤 (TBI) 后的生活质量 (QoL) 很重要，但有限的研究比较了 QoL 清单。在 2579 名 TBI 患者、骨科创伤对照组和健康朋友对照组参与者中，我们比较了为 TBI 患者开发的脑损伤后生活质量总体量表 (QOLIBRI-OS) 与生活满意度量表 (SWLS)，后者是一种指数一般的生活满意度。我们测试了 QOLIBRI-OS 的组差异（TBI 和骨科创伤与健康朋友对照）比 SWLS 更大的假设，并且 QOLIBRI-OS 会随着时间的推移在受伤组中表现出更大的变化，证明更多的相关性QOLIBRI-OS 对创伤性损伤恢复的影响。(1) 我们比较了组间差异（TBI vs. 骨科创伤对照 vs. 朋友控制）在 QoL 中由 SWLS 与 QOLIBRI-OS 索引，并且（2）表征了这三个组中这两个清单在 1 年内随时间的变化。我们的次要目标是描述 TBI 严重程度和 QoL 之间的关系。与健康的朋友对照组相比，对于 TBI 组（所有时间点）和骨科创伤对照组（2 周和 3 个月），QOLIBRI 反映出比 SWLS 更大的 QoL 降低。与 SWLS 相比，QOLIBRI-OS 在受伤组的损伤恢复过程中更好地捕获了 QoL 的预期改善，后者随着时间的推移表现出较小的变化。TBI 严重程度与自我报告的 QoL 并不一致或密切相关。结果表明，与 SWLS 相比，