Brain tumors are the most frequent solid cancer in the pediatric population. Owing to the rarity of environmental clues about their origin, it is tempting to consider these neoplasms as developmental processes gone awry. Our review will explore the heuristic power of this hypothesis and the influence of these findings on the clinical management.

中文翻译：

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小儿脑肿瘤是一种发育性疾病。

脑肿瘤是儿科人群中最常见的实体癌。由于关于它们起源的环境线索很少，人们很容易将这些肿瘤视为发育过程出错。我们的审查将探讨这一假设的启发性力量以及这些发现对临床管理的影响。