Clinical usefulness of a novel fluorescence technique for the intraoperative diagnosis of surgical margins in patients with breast cancer,British Journal of Surgery

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Clinical usefulness of a novel fluorescence technique for the intraoperative diagnosis of surgical margins in patients with breast cancer
British Journal of Surgery ( IF 8.6 ) Pub Date : 2021-06-30 , DOI: 10.1093/bjs/znab265
H Ueo _{1,

2} , H Ueo ₂ , I Minoura ₃ , A Gamachi ₄ , T Doi ₅ , M Yamaguchi ₆ , T Yamashita ₇ , H Tsuda ₈ , T Moriya ₉ , R Yamaguchi ₁₀ , Y Kozuka ₁₁ , T Sasaki ₁₂ , T Masuda ₁₃ , Y Kai ₂ , Y Kubota ₂ , Y Urano ₁₄ , M Mori ₁ , K Mimori ₁₃

Affiliation

Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Ueo Breast Cancer Hospital, Oita, Japan.
Goryo Chemical, Inc., Sapporo, Japan.
Department of Pathology, Almeida Memorial Hospital, Oita, Japan.
Breast Cancer Centre, Shonan Memorial Hospital, Kamakura, Japan.
Department of Breast Surgery, JCHO Kurume General Hospital, Kurume, Japan.
Department of Breast and Endocrine Surgery, Kanagawa Cancer Centre, Yokohama, Japan.
Department of Basic Pathology, National Defence Medical College, Tokorozawa, Japan.
Department of Pathology, Kawasaki Medical School, Kurashiki, Japan.
Department of Pathology and Laboratory Medicine, Kurume University Medical Centre, Kurume, Japan.
Department of Pathology, Mie University Hospital, Tsu, Japan.
Department of Next-Generation Pathology Information and Networking, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Department of Surgery, Kyushu University Beppu Hospital, Beppu, Japan.
Graduate School of Medicine and Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

In both 5- and 15-min data, FI was significantly higher in malignant tissues than in benign tissues. The diagnostic accuracy was similar at 5 and 15 min. Therefore, the 5-min FI was enough applying in the further analyses.

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