The controlled covalent functionalization of the graphene channel of a field effect transistor, based on interdigitated gold electrodes (source and drain), via electrochemical grafting, using specifically designed aryl diazonium species is demonstrated to allow the simple fabrication of a general platform for (bio)sensing applications. The electrochemical grafting of a protected ethynylphenyl diazonium salt leads to the deposition of only a monolayer on the graphene channel. This controlled covalent functionalization of the graphene channel results in a charge mobility of the GFET of 1739 ± 376 cm² V⁻¹ s⁻¹ and 1698 ± 536 cm² V⁻¹ s⁻¹ for the holes and electrons, respectively, allowing their utilization as (bio)sensors. After deprotection, a dense and compact ethynylphenyl monolayer is obtained and allows the immobilization of a wide range of (bio)molecules by a “click” chemistry coupling reaction (Huisgen 1,3-dipolar cycloaddition). This finding opens promising options for graphene-based (bio)sensing applications.

中文翻译：

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场效应晶体管石墨烯通道的受控共价功能化作为（生物）传感应用的理想平台

场效应晶体管的石墨烯通道的受控共价功能化，基于交叉金电极（源极和漏极），通过电化学接枝，使用专门设计的芳基重氮物种被证明可以简单地制造（生物）的通用平台传感应用。受保护的乙炔基苯基重氮盐的电化学接枝导致在石墨烯通道上仅沉积单层。石墨烯通道的这种受控共价功能化导致 GFET 的电荷迁移率为 1739 ± 376 cm ² V ^-1 s ^-1和 1698 ± 536 cm ² V ^-1 s ^-1分别用于空穴和电子，允许它们用作（生物）传感器。脱保护后，获得致密且致密的乙炔基苯基单层，并允许通过“点击”化学偶联反应（Huisgen 1,3-偶极环加成）固定各种（生物）分子。这一发现为基于石墨烯的（生物）传感应用开辟了有前景的选择。