An outbreak of acute encephalopathy occurred in pregnant ewes and their newborn lambs associated with consumption of Talisia esculenta fruits and bark. Clinical signs in 5 adult pregnant ewes included drooling, bloat, tachypnea, depression, ataxia, body shaking, difficulty in rising, and recumbency. Three neonatal lambs born to some of those ewes had similar clinical signs. No significant gross abnormalities were observed on autopsy. Histologically, neuronal necrosis, axonal and dendritic swelling, and loss of Purkinje neurons were observed in the cerebellum. The observation of similar neurologic clinical signs and lesions in pregnant ewes and their neonatal lambs suggests that the toxic principle of T. esculenta crosses the placenta and reaches the fetus.

怀孕母羊及其新生羔羊爆发了与食用塔利西亚果实和树皮有关的急性脑病。 5只成年怀孕母羊的临床症状包括流口水、腹胀、呼吸急促、抑郁、共济失调、身体颤抖、起身困难和躺卧。其中一些母羊所生的三只新生羔羊也有类似的临床症状。尸检时未观察到明显的肉眼异常。组织学上，在小脑中观察到神经元坏死、轴突和树突肿胀以及浦肯野神经元丧失。在怀孕母羊及其新生羔羊中观察到类似的神经临床症状和病变表明， T. esculenta的毒性原理穿过胎盘并到达胎儿。