In this study, six different organo-hydrogels containing agar-glycerol (AG)-based garlic oil (GO) were synthesized using two different crosslinkers (N,N, methylenebisacrylamide (MBA), glutaraldehyde (GA)) to ensure the controlled release of ceftriaxone (Ce) and carboplatin (Cp). Synthesized organo-hydrogels were characterized by FT-IR. Afterward, swelling behaviors were investigated in DI, tap water, ethanol, acetone, ethanol/DI water (1:1), acetone/DI water (1:1) and gasoline environments and different pH. As a result of hemolysis, blood clotting and antioxidant analysis, organo-hydrogels have been shown to have blood compatibility and antioxidant properties. Ce and Cp release properties of the prepared organo-hydrogels were also determined. The highest Ce release rate was obtained to be 37.8% for p (AG-g-GO)³ at pH 8.0 after 7 days. However, the highest Cp release rate was found to be 95.4% for p (AG-g-GO)³ at pH 7.4 after 1 day.

在这项研究中，使用两种不同的交联剂（N、N、亚甲基双丙烯酰胺（MBA）、戊二醛（GA））合成了六种不同的含有琼脂甘油（AG）基大蒜油（GO）的有机水凝胶，以确保控制释放头孢曲松 (Ce) 和卡铂 (Cp)。合成的有机水凝胶通过 FT-IR 表征。然后，研究了在去离子、自来水、乙醇、丙酮、乙醇/去离子水 (1:1)、丙酮/去离子水 (1:1) 和汽油环境和不同 pH 值下的溶胀行为。由于溶血、血液凝固和抗氧化分析，有机水凝胶已被证明具有血液相容性和抗氧化特性。还测定了制备的有机水凝胶的 Ce 和 Cp 释放特性。p (AG-g-GO) 的最高 Ce 释放率为 37.8%³ 7 天后 pH 值为 8.0。然而，发现1 天后p (AG-g-GO) ³在 pH 7.4 时的最高 Cp 释放率为 95.4% 。