Abstract: Pancreatic hepatoid carcinoma (HC) is a heterogeneous tumor with high degree of malignancy and poor prognosis, which display cytological and/or structural features of focal hepatocellular carcinoma (HCC). For the low incidence and atypical clinical symptoms, it is possible to be diagnosed as pancreatic cancer before operation, and mainly depending on the pathological examination. To the best of our knowledge, surgery combined with radiotherapy and chemotherapy is the common treatment of pancreatic HC. However, the curative effect and prognosis is poor. We report a case of 44-year-old woman with pancreatic HC treated with PD-1 receptor inhibitor and transarterial chemoembolization, whose clinical symptoms and laboratory indexes are significantly improved after treatment.

Keywords: pancreatic hepatoid carcinoma, surgical resection, transarterial chemoembolization, immunotherapy, case report


中文翻译：

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经动脉化疗栓塞联合免疫治疗胰腺肝样癌手术切除病例报告

摘要：胰腺肝样癌（HC）是一种恶性程度高、预后差的异质性肿瘤，具有局灶性肝细胞癌（HCC）的细胞学和/或结构特征。由于发病率低，临床症状不典型，术前可诊断为胰腺癌，主要依靠病理检查。据我们所知，手术联合放疗和化疗是胰腺 HC 的常见治疗方法。但疗效和预后较差。我们报告一例 44 岁胰腺 HC 女性患者，经 PD-1 受体抑制剂和经动脉化疗栓塞治疗后，临床症状和实验室指标均显着改善。

关键词： 胰腺肝样癌，手术切除，经动脉化疗栓塞，免疫治疗，病例报告