Providing accessible and effective healthcare solutions for people living in low- and middle-income countries, migrants, and indigenous people is central to reduce the global mental health treatment gap. Internet- and mobile-based interventions (IMI) are considered scalable psychological interventions to reduce the burden of mental disorders and are culturally adapted for implementation in these target groups. In October 2020, the databases PsycInfo, MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and Web of Science were systematically searched for studies that culturally adapted IMI for mental disorders. Among 9438 screened records, we identified 55 eligible articles. We extracted 17 content, methodological, and procedural components of culturally adapting IMI, aiming to consider specific situations and perspectives of the target populations. Adherence and effectiveness of the adapted IMI seemed similar to the original IMI; yet, no included study conducted a direct comparison. The presented taxonomy of cultural adaptation of IMI for mental disorders provides a basis for future studies investigating the relevance and necessity of their cultural adaptation.

PROSPERO registration number: CRD42019142320.

为低收入和中等收入国家的人们、移民和土著人民提供方便且有效的医疗保健解决方案对于缩小全球心理健康治疗差距至关重要。基于互联网和移动设备的干预措施（IMI）被认为是可扩展的心理干预措施，可减轻精神障碍的负担，并且在文化上适合在这些目标群体中实施。 2020 年 10 月，系统地检索了 PsycInfo、MEDLINE、Embase、Cochrane Central Register of Controlled Trials 和 Web of Science 数据库，以查找在文化上适应 IMI 治疗精神障碍的研究。在 9438 条筛选记录中，我们确定了 55 篇符合条件的文章。我们提取了文化适应 IMI 的 17 个内容、方法和程序组成部分，旨在考虑目标人群的具体情况和观点。改编后的 IMI 的依从性和有效性似乎与原始 IMI 相似；然而，没有纳入的研究进行直接比较。所提出的 IMI 对精神障碍的文化适应分类为未来研究其文化适应的相关性和必要性提供了基础。

PROSPERO 注册号：CRD42019142320。