This study evaluates the efficacy of palm oil-based nanoemulsion insecticides in thermal fogging applications against adult Ae. aegypti. The nanoemulsion formulations contained a palm oil methyl ester solvent, water, a non-ionic surfactant, and active ingredient deltamethrin, with nanoemulsion droplet diameters ranging from 362 to 382 nm. Knockdown and mortality rates of caged mosquitoes were measured at various distances up to 18 m from the spray nozzle. After 15 min of insecticide exposure, nanoemulsion insecticides achieved a knockdown rate of >97% at a spraying distance of 4 m, and the knockdown effect increased substantially with exposure time. At an 18 m spraying distance, the best nanoemulsion formulation, NanoEW8, achieved a high mosquito mortality rate of more than 80%, whereas the non-nanoemulsion and the commercial product reached only 14 and 8 m distances, respectively, for comparable mortality. The artificial neural network (ANN) was used to predict the mosquito knockdown distribution over the spraying distances and time intervals. The models predicted that NanoEW8 can still cause knockdown at a maximum distance of 61.5 m from the discharge point 60 min after spraying. The results established that Ae. aegypti was susceptible to the newly developed palm oil-based nanoemulsion insecticide, indicating a high potential for mosquito control.

本研究评估了基于棕榈油的纳米乳液杀虫剂在热雾应用中对成虫Ae的功效。埃及. 纳米乳液配方包含棕榈油甲酯溶剂、水、非离子表面活性剂和活性成分溴氰菊酯，纳米乳液液滴直径范围为 362 至 382 nm。在距喷嘴最远 18 m 的不同距离处测量了笼中蚊子的击倒率和死亡率。接触杀虫剂15 min后，纳米乳杀虫剂在4 m的喷洒距离下实现了> 97%的击倒率，并且击倒效果随着暴露时间的增加而显着增加。在 18 m 喷洒距离下，最佳纳米乳剂 NanoEW8 实现了超过 80% 的高蚊子死亡率，而非纳米乳剂和商业产品分别达到 14 米和 8 米的距离，死亡率相当。人工神经网络 (ANN) 用于预测喷洒距离和时间间隔内的蚊子击倒分布。模型预测 NanoEW8 在喷洒 60 分钟后仍可在距排放点 61.5 m 的最大距离处造成击倒。结果表明艾。aegypti对新开发的基于棕榈油的纳米乳液杀虫剂敏感，表明其具有很高的蚊子控制潜力。