Background Congenital esophageal atresia postoperative anastomotic stricture occurs in 30-50% of cases. Patients with severe dysphagia are treated with endoscopic balloon dilatation (EBD) and/or local injection of steroids, but many patients continue to experience frequent stricture. In this study, we investigated the transplantation of autologous oral mucosa-derived cell sheets (epithelial cell sheets) as a prophylactic treatment for congenital esophageal atresia postoperative anastomotic stricture.

中文翻译：

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首例自体口腔黏膜上皮片移植预防先天性食管闭锁吻合口再狭窄

背景先天性食管闭锁术后吻合口狭窄发生在 30-50% 的病例中。严重吞咽困难的患者接受内窥镜球囊扩张术 (EBD) 和/或局部注射类固醇治疗，但许多患者仍然经常出现狭窄。在这项研究中，我们研究了自体口腔黏膜衍生细胞片（上皮细胞片）的移植作为先天性食管闭锁术后吻合口狭窄的预防性治疗。