A chemiluminescence sensor array for discrimination of seven toxicants,Luminescence

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A chemiluminescence sensor array for discrimination of seven toxicants
Luminescence ( IF 3.2 ) Pub Date : 2021-08-25 , DOI: 10.1002/bio.4136
Ziqi Zhou ₁ , Yige Gong ₁ , Chao Zhang ₁ , Weifen Niu ₁

Affiliation

A chemiluminescence (CL) sensor array was developed based on 11 CL systems cross-combined by three luminescence reagents and four oxidants. Using the CL sensor array, we measured seven toxicants, including morphine, ketamine, diazepam, chlorpromazine, strychnine, paraquat, and fenpropathrin, which represent psychotropic drugs, sedatives and hypnotics, rodenticides, herbicides, and insecticides, respectively. The CL response pattern or ‘fingerprints’ were obtained for a given compound on the sensor array and then discriminated through principal component analysis. The established sensor array has been applied to real-life samples and the results showed that it possesses excellent discrimination.

中文翻译：

用于区分七种毒物的化学发光传感器阵列

基于由三种发光试剂和四种氧化剂交叉组合的 11 个 CL 系统开发了一种化学发光 (CL) 传感器阵列。使用 CL 传感器阵列，我们测量了七种毒物，包括吗啡、氯胺酮、地西泮、氯丙嗪、士的宁、百草枯和甲氰菊酯，它们分别代表精神药物、镇静催眠药、灭鼠剂、除草剂和杀虫剂。获得传感器阵列上给定化合物的 CL 响应模式或“指纹”，然后通过主成分分析进行区分。建立的传感器阵列已应用于现实生活中的样品，结果表明它具有出色的辨别力。

更新日期：2021-08-25

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