ABSTRACT

Purpose

To determine normal corneal eccentricity in a rural Japanese population and to examine factors associated with eccentricity value.

Methods

This used data from the Locomotive Syndrome and Health Outcome in Aizu Cohort Study (LOHAS) project between 2009 and 2012. Residents of Minamiaizu and Tadami in Fukushima, Japan, who were aged 40 years or over, were invited for a comprehensive eye examination. For 1371 patients with no history of internal eye surgery, corneal eccentricity was measured using a Pentacam.

Results

Of 1371 people recruited to the study, 1215 (1215 eyes) met the inclusion criteria. The overall mean eccentricity was 0.46 (SD = 0.18; range, −0.85 to 0.88). Corneal eccentricity was significantly associated with age, spherical equivalent, pupil diameter, anterior chamber angle, anterior chamber volume, and central corneal thickness, but not with gender or body mass index.

Conclusions

In this study, the normal cornea in this Japanese population was prolate. Corneal eccentricity was likely to decrease with increasing age. Also, spherical equivalent and other anterior segment parameters had an influence on corneal eccentricity. Corneal eccentricity measurements might be helpful in the diagnosis of corneal diseases and in calculations for intraocular lens implantation and corneal refractive surgery.

中文翻译：

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日本农村人口的角膜异常：会津队列研究 (LOHAS) 中的机车综合症和健康结果

摘要

目的

确定日本农村人口的正常角膜偏心率并检查与偏心率值相关的因素。

方法

这使用了 2009 年至 2012 年期间的会津队列研究 (LOHAS) 项目中的机车综合症和健康结果的数据。日本福岛市南会津和只见的 40 岁或以上的居民被邀请进行全面的眼科检查。对于没有内眼手术史的 1371 名患者，使用 Pentacam 测量角膜偏心率。

结果

在招募到该研究的 1371 人中，1215 人（1215 只眼睛）符合纳入标准。总体平均偏心率为 0.46（SD = 0.18；范围，-0.85 至 0.88）。角膜离心率与年龄、等效球体、瞳孔直径、前房角、前房容积和中央角膜厚度显着相关，但与性别或体重指数无关。

结论

在这项研究中，这个日本人群的正常角膜是扁长的。角膜离心率可能随着年龄的增长而减少。此外，等效球面和其他眼前节参数对角膜偏心率有影响。角膜偏心率测量可能有助于角膜疾病的诊断以及人工晶状体植入和角膜屈光手术的计算。