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Idiopathic Frozen Shoulder in Individuals with Diabetes: Association with Metabolic Control, Obesity, Antidiabetic Treatment and Demographic Characteristics in Adults with Type 1 or 2 Diabetes from the DPV Registry
Experimental and Clinical Endocrinology & Diabetes ( IF 1.6 ) Pub Date : 2021-08-23 , DOI: 10.1055/a-1543-8559
Alexander J Eckert 1, 2 , Maike Plaumann 3 , Sigrid Pehlke 4 , Christof Beck 5 , Steffen Mühldorfer 6 , Uwe Weickert 7 , Markus Laimer 8 , Martin Pfeifer 9 , Lars Stechemesser 10 , ReinhardW Holl 1, 2
Affiliation  

Aims To examine the association of frozen shoulder (FS) with demographic and diabetes-related outcomes in individuals with type 1 (T1D) or type 2 (T2D) diabetes aged ≥30 years. Materials and methods Multivariable logistic regression models, adjusted for demographics were used to calculate the proportion of FS in association with age, gender, diabetes duration, body mass index (BMI), haemoglobin A1C (HbA1c) and diabetes treatment. Results The unadjusted percentage of FS was higher in T1D compared to T2D (0.22% vs. 0.06%). In T1D, adjusted regression models revealed higher prevalence of FS in women than men (0.26 [0.20–0.34] % vs. 0.15 [0.11–0.21] %, p=0.010). No significant relationship of age and BMI with FS was found in both diabetes types. Longer diabetes duration was associated with a higher proportion of FS in T1D (p<0.001) and T2D (p=0.004). In T1D, HbA1c >7% was related to a higher proportion of FS compared to HbA1c ≤7% (0.25 [0.19–0.32] vs. 0.12 [0.08–0.20] %, p=0.007), while an inverse relationship was found in T2D (HbA1c ≤7%: 0.08 [0.07–0.10] vs. HbA1c >7%: 0.05 [0.04–0.06] %, p=0.001). Conclusions Different associations of FS with gender and HbA1c were observed for T1D and T2D; however, longer diabetes duration increases the risk for FS independent of diabetes type. Musculoskeletal diseases are still underreported in individuals with diabetes and awareness should be raised for FS as a specific diabetes complication.

中文翻译:

糖尿病患者的特发性肩周炎:DPV 登记处成人 1 型或 2 型糖尿病患者的代谢控制、肥胖、抗糖尿病治疗和人口学特征的关联

目的 研究年龄≥30 岁的 1 型 (T1D) 或 2 型 (T2D) 糖尿病患者的肩周炎 (FS) 与人口统计学和糖尿病相关结局的关系。材料和方法 使用针对人口统计学调整的多变量逻辑回归模型来计算与年龄、性别、糖尿病病程、体重指数 (BMI)、血红蛋白 A1C (HbA1c) 和糖尿病治疗相关的 FS 比例。结果 与 T2D 相比,T1D 中未调整的 FS 百分比更高(0.22% vs. 0.06%)。在 T1D 中,调整后的回归模型显示女性的 FS 患病率高于男性(0.26 [0.20–0.34] % vs. 0.15 [0.11–0.21] %,p=0.010)。在两种糖尿病类型中均未发现年龄和 BMI 与 FS 的显着关系。较长的糖尿病病程与较高比例的 FS 在 T1D (p<0.001) 和 T2D (p=0. 004)。在 T1D 中,与 HbA1c ≤7% 相比,HbA1c >7% 与更高比例的 FS 相关(0.25 [0.19–0.32] vs. 0.12 [0.08–0.20] %,p=0.007),而在T2D(HbA1c ≤7%:0.08 [0.07–0.10] 与 HbA1c >7%:0.05 [0.04–0.06]%,p=0.001)。结论 在 T1D 和 T2D 观察到 FS 与性别和 HbA1c 的不同关联;然而,较长的糖尿病病程会增加 FS 的风险,而与糖尿病类型无关。肌肉骨骼疾病在糖尿病患者中的报道仍然不足,应提高对 FS 作为特定糖尿病并发症的认识。001)。结论 在 T1D 和 T2D 观察到 FS 与性别和 HbA1c 的不同关联;然而,较长的糖尿病病程会增加 FS 的风险,而与糖尿病类型无关。肌肉骨骼疾病在糖尿病患者中的报道仍然不足,应提高对 FS 作为特定糖尿病并发症的认识。001)。结论 在 T1D 和 T2D 观察到 FS 与性别和 HbA1c 的不同关联;然而,较长的糖尿病病程会增加 FS 的风险,而与糖尿病类型无关。肌肉骨骼疾病在糖尿病患者中的报道仍然不足,应提高对 FS 作为特定糖尿病并发症的认识。
更新日期:2021-08-24
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