Gut microbiota composition may affect the central nervous system (CNS) and immune function. Several studies have recently examined the possible link between gut microbiota composition and multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Most of these studies agree that patients with MS suffer from dysbiosis. Moreover, an altered proportion of certain phyla of bacteria was detected in the digestive tracts of these patients compared to healthy individuals. This review article gathers information from research papers that have examined the relationship between gut microbiota composition and MS and its possible mechanisms.

肠道微生物群组成可能会影响中枢神经系统 (CNS) 和免疫功能。最近有几项研究检查了肠道微生物群组成与多发性硬化症 (MS) 及其动物模型实验性自身免疫性脑脊髓炎 (EAE) 之间的可能联系。这些研究中的大多数都同意 MS 患者患有生态失调。此外，与健康个体相比，在这些患者的消化道中检测到某些细菌门的比例发生了变化。这篇评论文章收集了研究论文中的信息，这些论文研究了肠道微生物群组成与 MS 之间的关系及其可能的机制。