Research on monogenic forms of autism spectrum disorder (autism) can inform our understanding of genetic contributions to the autism phenotype; yet, there is much to be learned about the pathways from gene to brain structure to behavior. This systematic review summarizes and evaluates research on brain magnetic resonance imaging (MRI) findings in monogenic conditions that have strong association with autism. This will improve understanding of the impact of genetic variability on brain structure and related behavioral traits in autism.

中文翻译：

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对与自闭症谱系障碍密切相关的单基因障碍的脑 MRI 结果的系统评价

对孤独症谱系障碍（孤独症）的单基因形式的研究可以帮助我们了解遗传对孤独症表型的贡献；然而，关于从基因到大脑结构再到行为的途径，还有很多东西需要学习。本系统综述总结并评估了与自闭症密切相关的单基因疾病中脑磁共振成像 (MRI) 发现的研究。这将提高对遗传变异对自闭症大脑结构和相关行为特征影响的理解。